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Histopathology of Preclinical Toxicity Studies, Third Edition: Interpretation and Relevance in Drug Safety Evaluation
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Binding: Hardcover
Dewey Decimal Number: 615.1901
EAN: 9780444527714
Edition: 3
ISBN: 0444527710
Label: Elsevier Science
Manufacturer: Elsevier Science
Number Of Items: 1
Number Of Pages: 960
Publication Date: March 23, 2007
Publisher: Elsevier Science
Studio: Elsevier Science
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Editorial Review:
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.NEW TO THE THIRD EDITION:
* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies
* General comments to each chapter about the relevance of pathological findings to humans
* Provides essential information that can help decide the relevance of particular lesions for patients
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